Triple dementia risk associated with multiple heart-related conditions: Research | Health

A large new study found that having multiple conditions affecting the heart is associated with a higher risk of dementia than a high genetic risk.

Led by the University of Oxford and the University of Exeter, this study is the largest to examine the relationship between several heart-related conditions and dementia, and is one of the few to look at the complex problem of multiple health conditions.

The paper, published in The Lancet Healthy Longitude, looks at data from over 200,000 people aged 60 or over and European descendants in UK Biobank. The international research team has identified those who have been diagnosed with cardiometabolic conditions, diabetes, stroke or heart attack, or any combination of these three and developed dementia.

Read also: HIV medicine can combat middle-aged memory loss: A study

Researchers found that within this study population, if a person had more than three of these conditions, their risk of dementia increased. People with all three conditions are three times more likely to develop dementia than people with a higher genetic risk.

Dr Xin Yu Tai, lead author and doctoral student at the University of Oxford, said: “Dementia is a major global problem, predicting that there will be 135 million people around the world by 2050. We have found that such cardiovascular conditions are linked. So whatever your genetic risk, you can potentially reduce the risk of dementia by taking care of heart and metabolic health throughout life. “

The team, which includes the University of Glasgow and the University of Michigan, found that nearly 20,000 UK biobank participants they studied identified one of three conditions. Just over 2,000 had two conditions and 122 had all three conditions.

Professor David Llewellyn, senior author, Professor of Clinical Epidemiology and Clinical Health at the University of Exeter, said: “Many studies look at the risk of a single condition in relation to dementia, but we know that health is more complex. Our study tells us that it is important to take care of their health and ensure that they are treated properly and to reduce their risk of dementia. “

The team divided 200,000 participants into three categories of genetic risk based on a comprehensive risk score that reflects the multiple genetic risk characteristics for individuals of European ancestry. They had brain imaging data for over 12,000 participants and found widespread damage throughout the brain for those with more than one cardiometabolic condition. In contrast, high genetic risk is associated with atrophy only in specific parts of the brain.

Dr. Kenneth M. Collins, co-author of the study, is a medical professor at the University of Michigan and Veteran Affairs on Arbor Healthcare System. Longa said: “Our research suggests that protecting the heart has significant benefits throughout life. After your heart is in place, you can engage in regular exercise, eat a healthy diet, and do everything possible to ensure blood pressure, blood sugar and cholesterol levels fall within the guidelines.”

Dr Sarah Emarisio, head of research at Alzheimer’s Research UK, said: “The evidence is clear that what is good for your heart is good for your head. The risk of developing a dementia is a combination of their age, their genes, and their lifestyle factors. Researchers are 60 years and older. Looking at age demographic data, they find out whether they have specific heart conditions and how their genetics influence their risk of developing dementia.

“These findings reiterate the importance of treating the causes of poor heart health, but have the added benefit of reducing the number of cases of dementia. .

“If anyone is worried about your heart or the health of your brain, please talk to your doctor.”

This story was published by Wire Agency Feed without modification to the text.

Leave a Comment