Monkeypox symptoms in UK patients differ from previous outbreaks: Lancet study

symptoms monkeypox Patients in the UK differ from those observed in previous outbreaks elsewhere in the world, according to a study published in Lancet Infectious Diseases Saturday magazine.

Researchers examined 54 patients who attended sexual health clinics in London, UK, and were diagnosed with monkeypox During a 12-day period in May this year.

The results indicate that patients in this group have a higher prevalence of skin lesions Genital and anal area and lower prevalence of fatigue and fever compared to previously studied monkeypox outbreaks.

Based on these findings, the researchers suggest that current case definitions of “possible cases” of monkeypox should be revised to help identify cases.

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They also predict a higher prevalence of genital skin lesions in patients and a higher incidence Sexually transmitted diseases This means that sexual health clinics are likely to see additional cases of monkeypox in the future.

Researchers are calling for additional resources to support services in managing this condition.

Currently, the United Kingdom and many other countries are experiencing a rapid increase in cases of monkeypox among individuals attending sexual health Niccolo Jerometti, from the NHS Foundation Trust in Chelsea and Westminster, said:

“Monkeypox is a new diagnosis within sexual health Jerometti said the setup and our study, the first of its kind to report cases from this outbreak in the UK, will support case discovery and clinical care in the future.

The researchers collected data from monkeypox patients at four sexual health centers in London, UK.

Confirmed cases were identified as individuals with laboratory-confirmed infection using RT-PCR assay. They recorded data about the patient’s travel history, sexual history, and clinical symptoms.

Individuals diagnosed with monkeypox were advised Isolation Procedures and subsequently evaluated regularly by telephone care examinations.

The 54 patients observed in this study represented 60 per cent of cases reported in the UK during the 12-day study period during May this year.

All but two of the patients in the group were not aware that they had been in contact with a known case and none reported traveling to Sub-Saharan Africabut many of them have recently visited other European countries.

All patients were identified as men with sex With the men there was an average age of 41, the researchers said.

Up to 90 percent of patients who answered questions about sexual activity reported at least one new sexual partner within the three weeks prior to onset of symptoms, and nearly all reported inconsistent use of condoms in the same time period.

More than half of the patients had more than five sexual partners in the 12 weeks before they were diagnosed with monkeypox, the researchers said.

All patients were symptomatic and had skin lesions. 94 percent of patients had at least one skin lesion in the genital or perianal skin.

Most of the patients were mildly ill and recovered during home isolation, but five required hospitalization because of this pain or infection of skin lesions.

Everyone improved and was discharged with an average of seven days of hospitalization.

“The common symptoms of skin lesions in the anal and penile regions, and the fact that a quarter of patients tested positive for gonorrhea or chlamydia at the same time as monkeypox infection, suggest that it is the transmission of monkeypox virus in this group that occurs from skin to skin, for example In the context of sexual activitysaid Ruth Byrne, of the NHS Hospital Trust in Chelsea and Westminster.

The researchers noted important differences in the clinical features of this group compared to previous cases reported from previous outbreaks in other countries.

A smaller proportion of patients in the group reported feeling weak, tired or have a fever The researchers said studies were done on previous outbreaks.

They also added that 18 percent of patients in the group reported no early symptoms before the skin lesions appeared.

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